Creative Biolabs Provides Monkey Disease Models for the Research of Cardiovascular and Metabolic Disorders

September 24 11:58 2019

New York, USA, September 24, 2019 Creative Biolabs, an eminent biotech company with a reputation for unparalleled modeling capabilities, and high-quality deliveries, provides a comprehensive list of non-human primate (NHPs) diseases models, generally called monkey models, including but not limited to Cardiovascular and Metabolic Disorders Model,

Immune Disease Model, Liver Disease Model, Neurological Disease Model, Renal Disease Model, Urogenital Disease Model.

 

As is known, animal models not only play a crucial role in the study of pathogenesis, progression, and immune responses in distinct human diseases, but also prepare insightful values on preclinical evaluation/review of many therapeutic agents, vaccines, medical devices, etc. Equipped with the most similar disease progression model to that of humans, monkey diseases models are known for the most accurate and convincing data for pathogenesis characterization as well as preclinical research.

 

Type I diabetes, type II diabetes, and diet-induced obesity are three common metabolic disorders diseases, posing a giant challenge against human healthcare accompanied by a highly increasing prevalence. For the sake of a successful preclinical program, Creative Biolabs provides typical cardiovascular and metabolic disorders models, which are the well-established NHP type I diabetes induced by systemic administration of streptozotocin (STZ) for Type I diabetes, and high-fat diet (HFD)-induced diabetic monkeys with lots of similarities to human diabetics for Type II diabetes.

 

A wide-ranging list of validating measures are used to evaluate the modeling outcomes and drug efficacy, including but not limited to:

 

Body weight, height, body mass index (BMI)

Oral glucose tolerance test (OGTT), intravenous glucose tolerance test (IVGTT)

Insulin tolerance test (ITT)

Graded glucose infusion (GGI)

Euglycemic clamping

GI-bypass and gastric emptying

Clinical chemistry metabolic profiling

 

“Our team has accumulated for more than ten years in animal models. These valuable experiences pave the way for the development of our exclusive NHP disease model platform.  All cost-effective services of the best quality are provided by our scientists based on the premise of the highest ethical standards of animal care and welfare,” said by the senior scientist at Creative Biolabs.

 

 

Besides Cardiovascular and Metabolic Disorders Model, the models for neurological diseases, renal diseases, and urogenital diseases are also available. More information can be reached at https://www.creative-biolabs.com/drug-discovery/therapeutics.

 

About Creative Biolabs

Creative Biolabs is one of the few companies who can offer integrated drug discovery services for clients all over the world. Talented and well-trained scientists are working closely with each other to realize the goal of our customers. To discover and develop the qualified medicines of tomorrow, the scientists, who are concentrating on every important aspect of the industry, especially for the drug discovery pipeline, are able to undertake the entire discovery pipeline but also pleased to offer specific service based on clients’ requirements. Creative Biolabs offers comprehensive services ranging from target identification and validation, hit identification, hit to lead, lead optimization to the investigational new drug (IND).

Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-619-7922
Address:45-1 Ramsey Road
City: Shirley
State: New York
Country: United States
Website: https://www.creative-biolabs.com/drug-discovery/therapeutics